TGFB1

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

1KLA, 1KLC, 1KLD, 3KFD, 4KV5


識別子
記号 ⇒TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta 1, IBDIMDE, TGF-beta1
外部IDOMIM: 190180 MGI: ⇒98725 HomoloGene: 540 GeneCards: TGFB1

遺伝子の位置 (ヒト)

染色体19番染色体 (ヒト)[1]

バンドデータ無し開始点41,301,587 bp[1]
終点41,353,922 bp[1]

遺伝子の位置 (マウス)

染色体7番染色体 (マウス)[2]

バンドデータ無し開始点25,386,427 bp[2]
終点25,404,502 bp[2]

RNA発現パターン



⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒type II transforming growth factor beta receptor binding
? ⇒protein N-terminus binding
? ⇒cytokine activity
? ⇒酵素結合
? ⇒growth factor activity
? ⇒抗原結合
? ⇒type I transforming growth factor beta receptor binding
? ⇒protein homodimerization activity
? ⇒protein serine/threonine kinase activator activity
? ⇒血漿タンパク結合
? ⇒protein heterodimerization activity
? ⇒type III transforming growth factor beta receptor binding
? ⇒transforming growth factor beta receptor binding
? ⇒identical protein binding

細胞の構成要素? ⇒細胞質
? ⇒細胞外領域
? ⇒細胞核
? ⇒微絨毛
? ⇒cell surface
? ⇒blood microparticle
? ⇒細胞膜
? ⇒secretory granule
? ⇒神経繊維
? ⇒neuronal cell body
? ⇒Golgi lumen
? ⇒platelet alpha granule lumen
? ⇒細胞外マトリックス
? ⇒細胞外空間

生物学的プロセス? ⇒positive regulation of histone deacetylation
? ⇒positive regulation of transcription regulatory region DNA binding
? ⇒ureteric bud development
? ⇒tolerance induction to self antigen
? ⇒positive regulation of protein phosphorylation
? ⇒内胚葉の発生
? ⇒response to cholesterol
? ⇒positive regulation of MAP kinase activity
? ⇒regulation of sodium ion transport
? ⇒response to progesterone
? ⇒negative regulation of cell cycle
? ⇒有機物への反応
? ⇒乳房発達
? ⇒T cell homeostasis
? ⇒negative regulation of ossification
? ⇒negative regulation of hyaluronan biosynthetic process
? ⇒タンパク質リン酸化
? ⇒T cell differentiation
? ⇒positive regulation of vascular permeability
? ⇒animal organ regeneration
? ⇒positive regulation of blood vessel endothelial cell migration
? ⇒negative regulation of epithelial cell proliferation
? ⇒regulation of binding
? ⇒inner ear development
? ⇒myelination
? ⇒negative regulation of macrophage cytokine production
? ⇒細胞増殖
? ⇒transforming growth factor beta receptor signaling pathway
? ⇒face morphogenesis
? ⇒negative regulation of cell population proliferation
? ⇒positive regulation of receptor clustering
? ⇒regulation of apoptotic process
? ⇒positive regulation of collagen biosynthetic process
? ⇒cellular response to transforming growth factor beta stimulus
? ⇒pathway-restricted SMAD protein phosphorylation
? ⇒regulation of DNA binding
? ⇒regulation of actin cytoskeleton reorganization
? ⇒negative regulation of fat cell differentiation
? ⇒positive regulation of protein metabolic process
? ⇒cell-cell junction organization
? ⇒negative regulation of myoblast differentiation
? ⇒positive regulation of protein kinase B signaling
? ⇒common-partner SMAD protein phosphorylation
? ⇒positive regulation of branching involved in ureteric bud morphogenesis
? ⇒SMAD protein signal transduction
? ⇒epidermal growth factor receptor signaling pathway
? ⇒macrophage derived foam cell differentiation
? ⇒negative regulation of blood vessel endothelial cell migration
? ⇒positive regulation of protein dephosphorylation
? ⇒extrinsic apoptotic signaling pathway
? ⇒negative regulation of extracellular matrix disassembly
? ⇒mitotic cell cycle checkpoint signaling
? ⇒positive regulation of fibroblast proliferation
? ⇒negative regulation of cell differentiation
? ⇒regulation of branching involved in mammary gland duct morphogenesis
? ⇒positive regulation of exit from mitosis
? ⇒negative regulation of transforming growth factor beta receptor signaling pathway
? ⇒遺伝子発現の負の調節
? ⇒morphogenesis of a branching structure
? ⇒regulation of SMAD protein signal transduction
? ⇒positive regulation of peptidyl-serine phosphorylation
? ⇒cell activation
? ⇒negative regulation of neuroblast proliferation
? ⇒positive regulation of transcription, DNA-templated
? ⇒細胞増殖
? ⇒negative regulation of T cell proliferation
? ⇒response to wounding