P53
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TP53

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

4QO1, 1A1U, 1AIE, 1C26, 1DT7, 1GZH, 1H26, 1HS5, 1KZY, 1MA3, 1OLG, 1OLH, 1PES, 1PET, 1SAE, 1SAF, 1SAK, 1SAL, 1TSR, 1TUP, 1UOL, 1XQH, 1YC5, 1YCQ, 1YCR, 1YCS, 2AC0, 2ADY, 2AHI, 2ATA, 2B3G, 2BIM, 2BIN, 2BIO, 2BIP, 2BIQ, 2FEJ, 2FOJ, 2FOO, 2GS0, 2H1L, 2H2D, 2H2F, 2H4F, 2H4H, 2H4J, 2H59, 2J0Z, 2J10, 2J11, 2J1W, 2J1X, 2J1Y, 2J1Z, 2J20, 2J21, 2K8F, 2L14, 2LY4, 2MEJ, 2MWO, 2MWP, 2MZD, 2OCJ, 2PCX, 2RUK, 2VUK, 2WGX, 2X0U, 2X0V, 2X0W, 2XWR, 2YBG, 2YDR, 2Z5S, 2Z5T, 3D05, 3D06, 3D07, 3D08, 3D09, 3D0A, 3DAB, 3DAC, 3IGK, 3IGL, 3KMD, 3KZ8, 3LW1, 3OQ5, 3PDH, 3Q01, 3Q05, 3Q06, 3SAK, 3TG5, 3TS8, 3ZME, 4AGL, 4AGM, 4AGN, 4AGO, 4AGP, 4AGQ, 4BUZ, 4BV2, 4HFZ, 4HJE, 4IBQ, 4IBS, 4IBT, 4IBU, 4IBV, 4IBW, 4IBY, 4IBZ, 4IJT, 4KVP, 4LO9, 4LOE, 4LOF, 4MZI, 4MZR, 4X34, 4ZZJ, 5AOL, 5ABA, 5AOK, 2MWY, 5A7B, 5AOJ, 5AOI, 5ECG, 5AB9, 4FZ3, 4RP6, 4XR8, 5AOM, 4RP7, 5HOU, 5HP0, 5HPD, 5LGY, 5G4M, 5G4O, 5G4N, 5BUA


識別子
記号 ⇒TP53, BCC7, LFS1, P53, TRP53, tumor protein p53, BMFS5, Genes, p53
外部IDOMIM: 191170 MGI: ⇒98834 HomoloGene: 460 GeneCards: TP53

遺伝子の位置 (ヒト)

染色体17番染色体 (ヒト)[1]

バンドデータ無し開始点7,661,779 bp[1]
終点7,687,538 bp[1]

遺伝子の位置 (マウス)

染色体11番染色体 (マウス)[2]

バンドデータ無し開始点69,471,185 bp[2]
終点69,482,699 bp[2]

RNA発現パターン



さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒protein N-terminus binding
? ⇒DNA-binding transcription factor activity
? ⇒protein self-association
? ⇒core promoter sequence-specific DNA binding
? ⇒DNA-binding transcription factor activity, RNA polymerase II-specific
? ⇒protein phosphatase binding
? ⇒ATP binding
? ⇒転写因子結合
? ⇒金属イオン結合
? ⇒protein phosphatase 2A binding
? ⇒酵素結合
? ⇒zinc ion binding
? ⇒クロマチン結合
? ⇒protease binding
? ⇒damaged DNA binding
? ⇒血漿タンパク結合
? ⇒histone acetyltransferase binding
? ⇒銅イオン結合
? ⇒プロテインキナーゼ結合
? ⇒シャペロン結合
? ⇒DNA-binding transcription activator activity, RNA polymerase II-specific
? ⇒receptor tyrosine kinase binding
? ⇒p53結合
? ⇒identical protein binding
? ⇒protein heterodimerization activity
? ⇒ubiquitin protein ligase binding
? ⇒RNA polymerase II transcription regulatory region sequence-specific DNA binding
? ⇒DNA結合
? ⇒RNA polymerase II cis-regulatory region sequence-specific DNA binding
? ⇒TFIID-class transcription factor complex binding
? ⇒mRNA 3'-UTR binding
? ⇒ヒストンデアセチラーゼ結合
? ⇒disordered domain specific binding
? ⇒promoter-specific chromatin binding
? ⇒histone deacetylase regulator activity
? ⇒protein homodimerization activity
? ⇒MDM2/MDM4 family protein binding

細胞の構成要素? ⇒細胞質
? ⇒ミトコンドリア
? ⇒細胞核
? ⇒核内構造体
? ⇒TFIID
? ⇒核マトリックス
? ⇒replication fork
? ⇒核小体
? ⇒小胞体
? ⇒核質
? ⇒ミトコンドリアマトリックス
? ⇒PML body
? ⇒細胞質基質
? ⇒細胞内
? ⇒transcription regulator complex
? ⇒高分子複合体
? ⇒site of double-strand break

生物学的プロセス? ⇒positive regulation of histone deacetylation
? ⇒DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
? ⇒周期的プロセス
? ⇒replicative senescence
? ⇒negative regulation of telomerase activity
? ⇒oligodendrocyte apoptotic process
? ⇒cellular response to DNA damage stimulus
? ⇒intrinsic apoptotic signaling pathway
? ⇒positive regulation of neuron apoptotic process
? ⇒regulation of mitochondrial membrane permeability
? ⇒positive regulation of reactive oxygen species metabolic process
? ⇒cellular response to ionizing radiation
? ⇒positive regulation of thymocyte apoptotic process
? ⇒negative regulation of helicase activity
? ⇒細胞周期
? ⇒Ras protein signal transduction
? ⇒細胞増殖
? ⇒cellular response to hypoxia
? ⇒negative regulation of cell population proliferation
? ⇒ヌクレオチド除去修復
? ⇒cellular response to glucose starvation
? ⇒regulation of transcription, DNA-templated
? ⇒response to antibiotic
? ⇒transcription, DNA-templated
? ⇒ER overload response
? ⇒positive regulation of transcription, DNA-templated
? ⇒negative regulation of cell growth
? ⇒intrinsic apoptotic signaling pathway by p53 class mediator
? ⇒positive regulation of peptidyl-tyrosine phosphorylation
? ⇒viral process
? ⇒response to gamma radiation
? ⇒negative regulation of fibroblast proliferation


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出典: フリー百科事典『ウィキペディア(Wikipedia)
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