MSH2

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

2O8B, 2O8C, 2O8D, 2O8E, 2O8F, 3THW, 3THX, 3THY, 3THZ


識別子
記号 ⇒MSH2, mutS homolog 2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2, hMMRCS2, MSH-2
外部IDOMIM: 609309 MGI: ⇒101816 HomoloGene: 210 GeneCards: MSH2

遺伝子の位置 (ヒト)

染色体2番染色体 (ヒト)[1]

バンドデータ無し開始点47,403,067 bp[1]
終点47,663,146 bp[1]

遺伝子の位置 (マウス)

染色体17番染色体 (マウス)[2]

バンドデータ無し開始点87,979,758 bp[2]
終点88,031,141 bp[2]

RNA発現パターン

⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒DNA結合
? ⇒ヌクレオチド結合
? ⇒protein homodimerization activity
? ⇒mismatched DNA binding
? ⇒dinucleotide insertion or deletion binding
? ⇒ADP binding
? ⇒centromeric DNA binding
? ⇒oxidized purine DNA binding
? ⇒single-stranded DNA binding
? ⇒damaged DNA binding
? ⇒ATPアーゼ活性
? ⇒protein C-terminus binding
? ⇒血漿タンパク結合
? ⇒single thymine insertion binding
? ⇒four-way junction DNA binding
? ⇒MutLalpha complex binding
? ⇒酵素結合
? ⇒二本鎖DNA結合
? ⇒dinucleotide repeat insertion binding
? ⇒ATP binding
? ⇒プロテインキナーゼ結合
? ⇒magnesium ion binding
? ⇒single guanine insertion binding
? ⇒guanine/thymine mispair binding
? ⇒Y-form DNA binding
? ⇒heteroduplex DNA loop binding
? ⇒double-strand/single-strand DNA junction binding
? ⇒ATP-dependent activity, acting on DNA
? ⇒クロマチン結合

細胞の構成要素? ⇒MutSbeta complex
? ⇒膜
? ⇒MutSalpha complex
? ⇒核質
? ⇒mismatch repair complex
? ⇒細胞核
? ⇒染色体

生物学的プロセス? ⇒negative regulation of neuron apoptotic process
? ⇒germ cell development
? ⇒男性生殖腺発生
? ⇒複製後修復
? ⇒determination of adult lifespan
? ⇒in utero embryonic development
? ⇒cellular response to DNA damage stimulus
? ⇒酸化的リン酸化
? ⇒maintenance of DNA repeat elements
? ⇒positive regulation of helicase activity
? ⇒somatic recombination of immunoglobulin gene segments
? ⇒intrinsic apoptotic signaling pathway in response to DNA damage
? ⇒negative regulation of DNA recombination
? ⇒somatic recombination of immunoglobulin genes involved in immune response
? ⇒DNAミスマッチ修復
? ⇒B cell differentiation
? ⇒B cell mediated immunity
? ⇒DNA修復
? ⇒positive regulation of isotype switching to IgA isotypes
? ⇒positive regulation of isotype switching to IgG isotypes
? ⇒double-strand break repair
? ⇒meiotic gene conversion