MLH1
PDBに登録されている構造
PDBオルソログ検索: RCSB
PDBのIDコード一覧
3RBN, 4P7A
識別子
記号 ⇒MLH1, mutL homolog 1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1
外部IDOMIM: 120436 MGI: ⇒101938 HomoloGene: 208 GeneCards: MLH1
遺伝子の位置 (マウス)
染色体9番染色体 (マウス)[1]
バンドデータ無し開始点111,057,296 bp[1]
終点111,100,859 bp[1]
RNA発現パターン
⇒さらなる参照発現データ
遺伝子オントロジー
分子機能? ⇒mismatched DNA binding
? ⇒クロマチン結合
? ⇒single-stranded DNA binding
? ⇒ATPアーゼ活性
? ⇒血漿タンパク結合
? ⇒MutSalpha complex binding
? ⇒ATP binding
? ⇒guanine/thymine mispair binding
? ⇒ヌクレオチド結合
? ⇒酵素結合
細胞の構成要素? ⇒キアズマ
? ⇒膜
? ⇒male germ cell nucleus
? ⇒核質
? ⇒染色体
? ⇒condensed nuclear chromosome
? ⇒シナプトネマ複合体
? ⇒MutLalpha complex
? ⇒細胞核
? ⇒condensed chromosome
? ⇒late recombination nodule
? ⇒mismatch repair complex
生物学的プロセス? ⇒nuclear-transcribed mRNA poly(A) tail shortening
? ⇒resolution of meiotic recombination intermediates
? ⇒somatic hypermutation of immunoglobulin genes
? ⇒reciprocal meiotic recombination
? ⇒meiotic telomere clustering
? ⇒male meiotic nuclear division
? ⇒meiotic metaphase I plate congression
? ⇒homologous chromosome segregation
? ⇒卵形成
? ⇒male meiosis chromosome segregation
? ⇒cellular response to DNA damage stimulus
? ⇒meiotic chromosome segregation
? ⇒homologous chromosome pairing at meiosis
? ⇒クラススイッチ
? ⇒精子形成
? ⇒intrinsic apoptotic signaling pathway in response to DNA damage
? ⇒somatic recombination of immunoglobulin gene segments
? ⇒negative regulation of mitotic recombination
? ⇒somatic recombination of immunoglobulin genes involved in immune response
? ⇒meiotic spindle midzone assembly
? ⇒DNAミスマッチ修復
? ⇒細胞周期
? ⇒double-strand break repair via nonhomologous end joining
? ⇒female meiosis chromosome segregation
? ⇒DNA修復
? ⇒positive regulation of isotype switching to IgA isotypes
? ⇒positive regulation of isotype switching to IgG isotypes
? ⇒減数分裂
? ⇒細菌への反応
出典: ⇒Amigo / QuickGO
オルソログ
種ヒトマウス
Entrez
4292
17350
Ensembl
⇒ENSMUSG00000032498
UniProt
⇒Q9JK91
RefSeq
(mRNA)
NM_000249
NM_001167617
NM_001167618
NM_001167619
NM_001258271
NM_001258273
NM_001258274
NM_026810
NM_001324522
RefSeq
(タンパク質)
NP_000240
NP_001161089
NP_001161090
NP_001161091
NP_001245200
NP_001245202
NP_001245203
NP_001341544
NP_001341546
NP_001341547
NP_001341548
NP_001341549
NP_001341550
NP_001341551
NP_001341552
NP_001341556
NP_001341557
NP_001341558
NP_001341559