IGF1R

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

1IGR, 1JQH, 1K3A, 1M7N, 1P4O, 2OJ9, 2ZM3, 3D94, 3F5P, 3I81, 3LVP, 3LW0, 3NW5, 3NW6, 3NW7, 3O23, 3QQU, 4D2R, 4XSS, 5HZN


識別子
記号 ⇒IGF1R, CD221, IGFIR, IGFR, JTK13, insulin like growth factor 1 receptor, Insulin-like growth factor 1，IGF-1R
外部IDOMIM: 147370 MGI: ⇒96433 HomoloGene: 30997 GeneCards: IGF1R

遺伝子の位置 (ヒト)

染色体15番染色体 (ヒト)[1]

バンドデータ無し開始点98,648,539 bp[1]
終点98,964,530 bp[1]

遺伝子の位置 (マウス)

染色体7番染色体 (マウス)[2]

バンドデータ無し開始点67,602,575 bp[2]
終点67,883,416 bp[2]

RNA発現パターン



⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒トランスフェラーゼ活性
? ⇒ヌクレオチド結合
? ⇒protein kinase activity
? ⇒insulin-like growth factor binding
? ⇒insulin receptor binding
? ⇒insulin binding
? ⇒キナーゼ活性
? ⇒phosphatidylinositol 3-kinase binding
? ⇒insulin-like growth factor-activated receptor activity
? ⇒血漿タンパク結合
? ⇒identical protein binding
? ⇒transmembrane receptor protein tyrosine kinase activity
? ⇒insulin receptor substrate binding
? ⇒protein tyrosine kinase activity
? ⇒ATP binding
? ⇒insulin-like growth factor I binding
? ⇒insulin-activated receptor activity

細胞の構成要素? ⇒integral component of membrane
? ⇒膜
? ⇒intracellular membrane-bounded organelle
? ⇒receptor complex
? ⇒細胞膜
? ⇒integral component of plasma membrane
? ⇒alphav-beta3 integrin-IGF-1-IGF1R complex
? ⇒insulin receptor complex
? ⇒神経繊維

生物学的プロセス? ⇒insulin receptor signaling pathway
? ⇒insulin-like growth factor receptor signaling pathway
? ⇒リン酸化
? ⇒transmembrane receptor protein tyrosine kinase signaling pathway
? ⇒positive regulation of cell migration
? ⇒negative regulation of apoptotic process
? ⇒protein tetramerization
? ⇒positive regulation of DNA replication
? ⇒タンパク質リン酸化
? ⇒regulation of JNK cascade
? ⇒免疫応答
? ⇒positive regulation of cell population proliferation
? ⇒peptidyl-tyrosine autophosphorylation
? ⇒自己リン酸化
? ⇒phosphatidylinositol 3-kinase signaling
? ⇒phosphatidylinositol-mediated signaling
? ⇒シグナル伝達
? ⇒positive regulation of phosphatidylinositol 3-kinase signaling
? ⇒glucose homeostasis
? ⇒positive regulation of protein-containing complex disassembly
? ⇒positive regulation of MAPK cascade
? ⇒解剖学的構造の発生
? ⇒positive regulation of protein kinase B signaling
? ⇒cellular response to glucose stimulus
? ⇒dendritic spine maintenance
? ⇒amyloid-beta clearance
? ⇒positive regulation of cold-induced thermogenesis