IGF1

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

1B9G, 1GZR, 1GZY, 1GZZ, 1H02, 1H59, 1IMX, 1PMX, 1TGR, 1WQJ, 2DSR, 2GF1, 3GF1, 3LRI, 1BQT, 4XSS


識別子
記号 ⇒IGF1, IGF-I, IGF1A, IGFI, MGF, insulin like growth factor 1, IGF
外部IDOMIM: 147440 MGI: ⇒96432 HomoloGene: 515 GeneCards: IGF1

遺伝子の位置 (ヒト)

染色体12番染色体 (ヒト)[1]

バンドデータ無し開始点102,395,874 bp[1]
終点102,481,744 bp[1]

遺伝子の位置 (マウス)

染色体10番染色体 (マウス)[2]

バンドデータ無し開始点87,694,127 bp[2]
終点87,772,904 bp[2]

RNA発現パターン





⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒ホルモン活性
? ⇒insulin receptor binding
? ⇒growth factor activity
? ⇒integrin binding
? ⇒血漿タンパク結合
? ⇒insulin-like growth factor receptor binding

細胞の構成要素? ⇒細胞外領域
? ⇒exocytic vesicle
? ⇒insulin-like growth factor binding protein complex
? ⇒platelet alpha granule lumen
? ⇒insulin-like growth factor ternary complex
? ⇒alphav-beta3 integrin-IGF-1-IGF1R complex
? ⇒細胞膜
? ⇒細胞外空間

生物学的プロセス? ⇒positive regulation of transcription regulatory region DNA binding
? ⇒骨格系発生
? ⇒positive regulation of glucose import
? ⇒筋発生
? ⇒positive regulation of Ras protein signal transduction
? ⇒response to heat
? ⇒positive regulation of cardiac muscle hypertrophy
? ⇒positive regulation of smooth muscle cell migration
? ⇒DNA複製
? ⇒positive regulation of insulin-like growth factor receptor signaling pathway
? ⇒phosphatidylinositol 3-kinase signaling
? ⇒positive regulation of DNA binding
? ⇒Ras protein signal transduction
? ⇒細胞増殖
? ⇒positive regulation of mitotic nuclear division
? ⇒positive regulation of trophectodermal cell proliferation
? ⇒positive regulation of glycogen biosynthetic process
? ⇒positive regulation of fibroblast proliferation
? ⇒ERK1 and ERK2 cascade
? ⇒negative regulation of extrinsic apoptotic signaling pathway
? ⇒cell activation
? ⇒negative regulation of oocyte development
? ⇒positive regulation of transcription, DNA-templated
? ⇒bone mineralization involved in bone maturation
? ⇒positive regulation of peptidyl-tyrosine phosphorylation
? ⇒positive regulation of MAPK cascade
? ⇒proteoglycan biosynthetic process
? ⇒positive regulation of activated T cell proliferation
? ⇒positive regulation of epithelial cell proliferation
? ⇒negative regulation of release of cytochrome c from mitochondria
? ⇒タンパク質の安定化
? ⇒myotube cell development
? ⇒positive regulation of DNA replication
? ⇒myoblast proliferation
? ⇒skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
? ⇒positive regulation of protein secretion
? ⇒positive regulation of glycoprotein biosynthetic process