HLA-E

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

3CII, 1KPR, 1KTL, 1MHE, 2ESV, 3AM8, 3BZE, 3BZF, 3CDG


識別子
記号 ⇒HLA-E, EA1.2, EA2.1, HLA-6.2, MHC, QA1, major histocompatibility complex, class I, E
外部IDOMIM: 143010 MGI: ⇒95957 HomoloGene: 134018 GeneCards: HLA-E

遺伝子の位置 (ヒト)

染色体6番染色体 (ヒト)[1]

バンドデータ無し開始点30,489,509 bp[1]
終点30,494,194 bp[1]

遺伝子の位置 (マウス)

染色体17番染色体 (マウス)[2]

バンドデータ無し開始点36,340,665 bp[2]
終点36,343,747 bp[2]

RNA発現パターン





⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒beta-2-microglobulin binding
? ⇒MHC class I protein binding
? ⇒受容体結合
? ⇒natural killer cell lectin-like receptor binding
? ⇒peptide antigen binding
? ⇒T cell receptor binding

細胞の構成要素? ⇒integral component of membrane
? ⇒phagocytic vesicle membrane
? ⇒early endosome membrane
? ⇒膜
? ⇒MHC class Ib protein complex
? ⇒ゴルジ膜
? ⇒細胞膜
? ⇒cell surface
? ⇒MHC class I protein complex
? ⇒ER to Golgi transport vesicle membrane
? ⇒integral component of lumenal side of endoplasmic reticulum membrane
? ⇒エキソソーム
? ⇒recycling endosome membrane

生物学的プロセス? ⇒antigen processing and presentation
? ⇒adaptive immune response
? ⇒antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
? ⇒CD8-positive, alpha-beta T cell activation
? ⇒interferon-gamma-mediated signaling pathway
? ⇒免疫系プロセス
? ⇒antigen processing and presentation of peptide antigen via MHC class I
? ⇒positive regulation of T cell mediated cytotoxicity
? ⇒positive regulation of TRAIL production
? ⇒positive regulation of interleukin-4 production
? ⇒antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
? ⇒protection from natural killer cell mediated cytotoxicity
? ⇒positive regulation of interleukin-13 production
? ⇒type I interferon signaling pathway
? ⇒免疫応答