FMR1

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

2BKD, 2FMR, 2LA5, 2QND, 4OVA, 4QVZ, 4QW2, 5DE5, 5DE8, 5DEA


識別子
記号 ⇒FMR1, FMRP, FRAXA, POF, POF1, fragile X mental retardation 1, FMRP translational regulator 1, fragile X messenger ribonucleoprotein 1
外部IDOMIM: 309550 MGI: ⇒95564 HomoloGene: 1531 GeneCards: FMR1

遺伝子の位置 (ヒト)

染色体X染色体[1]

バンドデータ無し開始点147,911,919 bp[1]
終点147,951,125 bp[1]

遺伝子の位置 (マウス)

染色体X染色体 (マウス)[2]

バンドデータ無し開始点67,722,147 bp[2]
終点67,761,569 bp[2]

RNA発現パターン



⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒protein homodimerization activity
? ⇒poly(U) RNA binding
? ⇒ribosome binding
? ⇒poly(G) binding
? ⇒血漿タンパク結合
? ⇒protein heterodimerization activity
? ⇒核酸結合
? ⇒translation initiation factor binding
? ⇒mRNA結合
? ⇒G-quadruplex RNA binding
? ⇒RNA strand annealing activity
? ⇒siRNA binding
? ⇒miRNA binding
? ⇒mRNA 3'-UTR binding
? ⇒mRNA 5'-UTR binding
? ⇒translation repressor activity
? ⇒microtubule binding
? ⇒クロマチン結合
? ⇒methylated histone binding
? ⇒sequence-specific mRNA binding
? ⇒transmembrane transporter binding
? ⇒RNA stem-loop binding
? ⇒dynein complex binding
? ⇒RNA結合
? ⇒identical protein binding
? ⇒translation regulator activity

細胞の構成要素? ⇒細胞質
? ⇒axon terminus
? ⇒樹状突起スパイン
? ⇒核質
? ⇒SMN complex
? ⇒mRNA cap binding complex
? ⇒樹状突起
? ⇒核小体
? ⇒neuron projection
? ⇒cytoplasmic ribonucleoprotein granule
? ⇒細胞核
? ⇒polysomal ribosome
? ⇒細胞体
? ⇒perinuclear region of cytoplasm
? ⇒リボ核タンパク質
? ⇒シナプス後肥厚
? ⇒chromocenter
? ⇒神経繊維
? ⇒細胞結合
? ⇒neuronal ribonucleoprotein granule
? ⇒filopodium tip
? ⇒postsynaptic membrane
? ⇒ポリリボソーム
? ⇒カハール体
? ⇒染色体
? ⇒成長円錐
? ⇒セントロメア
? ⇒growth cone filopodium
? ⇒viral replication complex
? ⇒細胞膜
? ⇒extrinsic component of plasma membrane
? ⇒glial cell projection
? ⇒cell projection
? ⇒膜
? ⇒dendritic filopodium
? ⇒presynaptic membrane
? ⇒presynapse
? ⇒postsynapse
? ⇒シナプス
? ⇒細胞質基質
? ⇒messenger ribonucleoprotein complex
? ⇒ストレス顆粒
? ⇒リボ核タンパク質顆粒
? ⇒neuronal cell body
? ⇒dendritic spine neck
? ⇒axon cytoplasm

生物学的プロセス? ⇒negative regulation of translational initiation
? ⇒regulation of dendritic spine development
? ⇒positive regulation of intracellular transport of viral material
? ⇒cellular response to virus
? ⇒RNAスプライシング
? ⇒regulation of gene silencing by miRNA
? ⇒cellular response to hydroxyurea
? ⇒regulation of neurotransmitter secretion
? ⇒positive regulation of gene silencing by miRNA
? ⇒神経系発生
? ⇒cellular response to DNA damage stimulus
? ⇒遺伝子サイレンシング
? ⇒mRNA processing
? ⇒mRNA transport
? ⇒positive regulation of proteasomal protein catabolic process
? ⇒viral process
? ⇒regulation of mRNA stability
? ⇒positive regulation of response to DNA damage stimulus
? ⇒positive regulation of dendritic spine development
? ⇒regulation of filopodium assembly
? ⇒negative regulation of cytoplasmic translation
? ⇒regulation of translation
? ⇒regulation of alternative mRNA splicing, via spliceosome
? ⇒regulation of neuronal action potential
? ⇒positive regulation of mRNA binding
? ⇒cellular response to UV
? ⇒modulation by host of viral RNA genome replication
? ⇒glutamate receptor signaling pathway
? ⇒negative regulation of long-term synaptic depression
? ⇒positive regulation of filopodium assembly
? ⇒negative regulation of synaptic vesicle exocytosis
? ⇒positive regulation of receptor internalization