PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

1CDH, 1CDI, 1CDJ, 1CDU, 1CDY, 1G9M, 1G9N, 1GC1, 1JL4, 1Q68, 1RZJ, 1RZK, 1WIO, 1WIP, 1WIQ, 2B4C, 2JKR, 2JKT, 2KLU, 2NXY, 2NXZ, 2NY0, 2NY1, 2NY2, 2NY3, 2NY4, 2NY5, 2NY6, 2QAD, 3B71, 3CD4, 3JWD, 3JWO, 3LQA, 3O2D, 3S5L, 3T0E, 4JM2, 1WBR, 3S4S, 4H8W, 4P9H, 4Q6I, 4R2G, 4R4H, 4RQS, 3J70, 5A7X, 5A8H, 5CAY


識別子
記号 ⇒CD4, CD4mut, CD4 molecule, OKT4D, IMD79
外部IDOMIM: 186940 MGI: ⇒88335 HomoloGene: 513 GeneCards: CD4

遺伝子の位置 (ヒト)

染色体12番染色体 (ヒト)[1]

バンドデータ無し開始点6,786,858 bp[1]
終点6,820,799 bp[1]

遺伝子の位置 (マウス)

染色体6番染色体 (マウス)[2]

バンドデータ無し開始点124,841,655 bp[2]
終点124,865,184 bp[2]

遺伝子オントロジー
分子機能? ⇒膜貫通シグナル伝達受容体活性
? ⇒virus receptor activity
? ⇒protein homodimerization activity
? ⇒zinc ion binding
? ⇒extracellular matrix structural constituent
? ⇒酵素結合
? ⇒immunoglobulin binding
? ⇒血漿タンパク結合
? ⇒coreceptor activity
? ⇒interleukin-16 binding
? ⇒interleukin-16 receptor activity
? ⇒MHC class II protein binding
? ⇒identical protein binding
? ⇒protein tyrosine kinase binding
? ⇒シグナル伝達受容体活性
? ⇒プロテインキナーゼ結合
? ⇒受容体結合

細胞の構成要素? ⇒endoplasmic reticulum lumen
? ⇒integral component of membrane
? ⇒early endosome
? ⇒膜
? ⇒cell surface
? ⇒endoplasmic reticulum membrane
? ⇒脂質ラフト
? ⇒T cell receptor complex
? ⇒external side of plasma membrane
? ⇒細胞膜
? ⇒clathrin-coated vesicle membrane
? ⇒integral component of plasma membrane

生物学的プロセス? ⇒transmembrane receptor protein tyrosine kinase signaling pathway
? ⇒defense response to Gram-negative bacterium
? ⇒positive regulation of protein kinase activity
? ⇒mitigation of host defenses by virus
? ⇒positive regulation of calcium-mediated signaling
? ⇒シグナル伝達
? ⇒helper T cell enhancement of adaptive immune response
? ⇒T cell selection
? ⇒エストラジオールへの反応
? ⇒induction by virus of host cell-cell fusion
? ⇒adaptive immune response
? ⇒response to vitamin D
? ⇒T cell differentiation
? ⇒細胞表面受容体シグナル伝達経路
? ⇒positive regulation of T cell proliferation
? ⇒positive regulation of peptidyl-tyrosine phosphorylation
? ⇒enzyme linked receptor protein signaling pathway
? ⇒T cell activation
? ⇒positive regulation of T cell activation
? ⇒maintenance of protein location in cell
? ⇒サイトカイン産生
? ⇒T cell receptor signaling pathway
? ⇒免疫系プロセス
? ⇒positive regulation of calcium ion transport into cytosol
? ⇒regulation of T cell activation
? ⇒免疫応答
? ⇒細胞接着
? ⇒viral process
? ⇒fusion of virus membrane with host plasma membrane
? ⇒membrane organization
? ⇒positive regulation of protein phosphorylation
? ⇒positive regulation of kinase activity
? ⇒interleukin-15-mediated signaling pathway
? ⇒positive regulation of I-kappaB kinase/NF-kappaB signaling
? ⇒positive regulation of MAPK cascade
? ⇒positive regulation of monocyte differentiation
? ⇒positive regulation of transcription, DNA-templated
? ⇒positive regulation of viral entry into host cell
? ⇒regulation of calcium ion transport
? ⇒positive regulation of ERK1 and ERK2 cascade
? ⇒cellular response to granulocyte macrophage colony-stimulating factor stimulus
? ⇒サイトカイン媒介シグナル伝達経路
? ⇒macrophage differentiation

出典: ⇒Amigo / QuickGO

オルソログ
種ヒトマウス
Entrez

920

12504

Ensembl

⇒ENSG00000010610

⇒ENSMUSG00000023274

UniProt

⇒P01730

⇒P06332

RefSeq
(mRNA)

NM_000616
NM_001195014
NM_001195015
NM_001195016
NM_001195017

NM_001382705
NM_001382706
NM_001382707
NM_001382714

NM_013488

RefSeq
(タンパク質)

NP_000607
NP_001181943
NP_001181944
NP_001181945
NP_001181946

NP_001369634
NP_001369635
NP_001369636
NP_001369643

NP_038516

場所
(UCSC)Chr 12: 6.79 ? 6.82 MbChr 12: 124.84 ? 124.87 Mb
PubMed検索[3][4]
ウィキデータ

閲覧/編集 ヒト閲覧/編集 マウス

分子生物学において、CD4 (cluster of differentiation 4) とはいわゆるヘルパーT細胞、単球、マクロファージ、樹状細胞などの免疫系細胞が細胞表面に発現している糖タンパクで細胞表面抗原の1つである。