BRCA1

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

1JM7, 1JNX, 1N5O, 1OQA, 1T15, 1T29, 1T2U, 1T2V, 1Y98, 2ING, 3COJ, 3K0H, 3K0K, 3K15, 3PXA, 3PXB, 3PXC, 3PXD, 3PXE, 4IFI, 4IGK, 4JLU, 4OFB, 4U4A, 4Y18, 4Y2G


識別子
記号 ⇒BRCA1, breast cancer 1, early onset, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53, FANCS, breast cancer 1, DNA repair associated, BRCA1 DNA repair associated, Genes
外部IDOMIM: 113705 MGI: ⇒104537 HomoloGene: 5276 GeneCards: BRCA1

遺伝子の位置 (ヒト)

染色体17番染色体 (ヒト)[1]

バンドデータ無し開始点43,044,295 bp[1]
終点43,170,245 bp[1]

遺伝子の位置 (マウス)

染色体11番染色体 (マウス)[2]

バンドデータ無し開始点101,379,590 bp[2]
終点101,442,781 bp[2]

RNA発現パターン



⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒tubulin binding
? ⇒金属イオン結合
? ⇒酵素結合
? ⇒zinc ion binding
? ⇒damaged DNA binding
? ⇒血漿タンパク結合
? ⇒transcription coactivator activity
? ⇒androgen receptor binding
? ⇒RNA結合
? ⇒ubiquitin protein ligase binding
? ⇒ubiquitin-protein transferase activity
? ⇒DNA結合
? ⇒トランスフェラーゼ活性
? ⇒RNA polymerase binding
? ⇒identical protein binding

細胞の構成要素? ⇒BRCA1-BARD1 complex
? ⇒condensed nuclear chromosome
? ⇒BRCA1-A complex
? ⇒ubiquitin ligase complex
? ⇒細胞膜
? ⇒核質
? ⇒condensed chromosome
? ⇒細胞質
? ⇒染色体
? ⇒細胞核
? ⇒lateral element
? ⇒高分子複合体
? ⇒リボ核タンパク質

生物学的プロセス? ⇒response to ionizing radiation
? ⇒centrosome cycle
? ⇒染色体分離
? ⇒protein K6-linked ubiquitination
? ⇒intrinsic apoptotic signaling pathway in response to DNA damage
? ⇒細胞周期
? ⇒double-strand break repair via nonhomologous end joining
? ⇒アポトーシス
? ⇒regulation of apoptotic process
? ⇒regulation of gene expression by genetic imprinting
? ⇒regulation of transcription, DNA-templated
? ⇒negative regulation of fatty acid biosynthetic process
? ⇒transcription, DNA-templated
? ⇒regulation of transcription by RNA polymerase III
? ⇒fatty acid biosynthetic process
? ⇒regulation of DNA methylation
? ⇒negative regulation of intracellular estrogen receptor signaling pathway
? ⇒protein autoubiquitination
? ⇒positive regulation of histone H3-K9 methylation
? ⇒DNA recombination
? ⇒positive regulation of angiogenesis
? ⇒response to estrogen
? ⇒cellular response to indole-3-methanol
? ⇒negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
? ⇒negative regulation of transcription, DNA-templated
? ⇒positive regulation of protein ubiquitination
? ⇒androgen receptor signaling pathway
? ⇒negative regulation of centriole replication
? ⇒複製後修復
? ⇒脂質代謝
? ⇒cellular response to tumor necrosis factor
? ⇒positive regulation of DNA repair
? ⇒脂肪酸代謝
? ⇒positive regulation of gene expression
? ⇒negative regulation of histone H3-K4 methylation
? ⇒regulation of cell population proliferation
? ⇒negative regulation of reactive oxygen species metabolic process
? ⇒positive regulation of vascular endothelial growth factor production
? ⇒DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
? ⇒positive regulation of transcription by RNA polymerase II
? ⇒positive regulation of histone H4-K20 methylation
? ⇒DNA double-strand break processing
? ⇒double-strand break repair via homologous recombination
? ⇒negative regulation of histone acetylation
? ⇒protein ubiquitination
? ⇒positive regulation of histone H3-K4 methylation
? ⇒DNA修復
? ⇒double-strand break repair
? ⇒positive regulation of histone acetylation
? ⇒dosage compensation by inactivation of X chromosome
? ⇒negative regulation of histone H3-K9 methylation
? ⇒positive regulation of histone H3-K9 acetylation
? ⇒positive regulation of transcription, DNA-templated
? ⇒chordate embryonic development
? ⇒positive regulation of histone H4-K16 acetylation
? ⇒cellular response to DNA damage stimulus
? ⇒protein deubiquitination
? ⇒DNA複製
? ⇒mitotic G2/M transition checkpoint
? ⇒regulation of transcription by RNA polymerase II
? ⇒negative regulation of G0 to G1 transition
? ⇒transcription by RNA polymerase II
? ⇒mitotic G2 DNA damage checkpoint signaling