FGF2

PDBに登録されている構造
PDBオルソログ検索: RCSB PDBe PDBj

PDBのIDコード一覧

1BAS, 1BFB, 1BFC, 1BFF, 1BFG, 1BLA, 1BLD, 1CVS, 1EV2, 1FGA, 1FQ9, 1II4, 1IIL, 2BFH, 2FGF, 2M49, 4FGF, 4OEE, 4OEF, 4OEG


識別子
記号 ⇒FGF2, BFGF, FGF-2, FGFB, HBGF-2, fibroblast growth factor 2
外部IDOMIM: 134920 MGI: ⇒95516 HomoloGene: 1521 GeneCards: FGF2

遺伝子の位置 (ヒト)

染色体4番染色体 (ヒト)[1]

バンドデータ無し開始点122,826,708 bp[1]
終点122,898,236 bp[1]

遺伝子の位置 (マウス)

染色体3番染色体 (マウス)[2]

バンドデータ無し開始点37,402,495 bp[2]
終点37,464,257 bp[2]

RNA発現パターン



⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒cytokine activity
? ⇒heparin binding
? ⇒fibroblast growth factor receptor binding
? ⇒血漿タンパク結合
? ⇒nuclear receptor coactivator activity
? ⇒chemoattractant activity
? ⇒growth factor activity
? ⇒protein tyrosine kinase activity
? ⇒phosphatidylinositol-4,5-bisphosphate 3-kinase activity
? ⇒1-phosphatidylinositol-3-kinase activity
? ⇒receptor-receptor interaction
? ⇒integrin binding

細胞の構成要素? ⇒細胞外領域
? ⇒細胞核
? ⇒細胞外空間

生物学的プロセス? ⇒release of sequestered calcium ion into cytosol
? ⇒細胞分化
? ⇒negative regulation of fibroblast migration
? ⇒hyaluronan catabolic process
? ⇒positive regulation of endothelial cell proliferation
? ⇒positive regulation of MAP kinase activity
? ⇒negative regulation of blood vessel endothelial cell migration
? ⇒positive regulation of endothelial cell chemotaxis to fibroblast growth factor
? ⇒somatic stem cell population maintenance
? ⇒positive regulation of phospholipase C activity
? ⇒extracellular matrix organization
? ⇒傷の治癒
? ⇒negative regulation of cell death
? ⇒regulation of angiogenesis
? ⇒神経系発生
? ⇒cell migration involved in sprouting angiogenesis
? ⇒MAPK cascade
? ⇒positive regulation of angiogenesis
? ⇒positive regulation of phosphatidylinositol 3-kinase activity
? ⇒positive regulation of transcription, DNA-templated
? ⇒走化性
? ⇒fibroblast growth factor receptor signaling pathway
? ⇒chondroblast differentiation
? ⇒多細胞個体の発生
? ⇒growth factor dependent regulation of skeletal muscle satellite cell proliferation
? ⇒branching involved in ureteric bud morphogenesis
? ⇒positive regulation of cardiac muscle cell proliferation
? ⇒embryonic morphogenesis
? ⇒血管新生
? ⇒positive regulation of cell fate specification
? ⇒animal organ morphogenesis
? ⇒regulation of endothelial cell chemotaxis to fibroblast growth factor
? ⇒phosphatidylinositol biosynthetic process
? ⇒イノシトールリン酸生合成プロセス
? ⇒negative regulation of wound healing
? ⇒Ras protein signal transduction
? ⇒positive regulation of cell division
? ⇒シグナル伝達
? ⇒positive regulation of transcription by RNA polymerase II
? ⇒positive chemotaxis
? ⇒phosphatidylinositol phosphate biosynthetic process
? ⇒peptidyl-tyrosine phosphorylation
? ⇒positive regulation of sprouting angiogenesis
? ⇒positive regulation of cell population proliferation
? ⇒phosphatidylinositol-3-phosphate biosynthetic process
? ⇒stem cell proliferation
? ⇒regulation of signaling receptor activity
? ⇒positive regulation of protein kinase B signaling
? ⇒サイトカイン媒介シグナル伝達経路
? ⇒positive regulation of blood vessel endothelial cell migration
? ⇒positive regulation of ERK1 and ERK2 cascade
? ⇒positive regulation of vascular associated smooth muscle cell proliferation
? ⇒positive regulation of vascular endothelial cell proliferation
? ⇒positive regulation of cell migration involved in sprouting angiogenesis
? ⇒傍分泌シグナル伝達
? ⇒positive regulation of DNA biosynthetic process
? ⇒positive regulation of endothelial cell chemotaxis

出典: ⇒Amigo / QuickGO

オルソログ
種ヒトマウス
Entrez

2247

14173

Ensembl

⇒ENSG00000138685

⇒ENSMUSG00000037225

UniProt

⇒P09038

⇒P15655

RefSeq
(mRNA)

NM_002006
NM_001361665

NM_008006

RefSeq
(タンパク質)

NP_001997
NP_001348594

NP_032032

場所
(UCSC)Chr 4: 122.83 ? 122.9 MbChr 4: 37.4 ? 37.46 Mb
PubMed検索[3][4]
ウィキデータ

閲覧/編集 ヒト閲覧/編集 マウス

塩基性線維芽細胞増殖因子（えんきせいせんいがさいぼうぞうしょくいんし、英: basic fibroblast growth factor、略称: bFGF）またはFGF2、FGF-βは、FGF2遺伝子によってコードされる成長因子であり、シグナル伝達タンパク質である[5][6]。