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葉酸

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^ “妊娠前からはじめる妊産婦のための食生活指針 ?妊娠前から、健康なからだづくりを? 解説要領” (pdf). 厚生労働省. 2022年3月17日閲覧。
^ “平成 30 年度子ども・子育て支援推進調査研究事業妊娠・出産に当たっての適切な栄養・食生活に関する調査報告書” (pdf). 株式会社日本総合研究所. 2022年3月17日閲覧。
^ L. M. De-Regil, (2015). “Effects and safety of periconceptional oral folate supplementation for preventing birth defects”. Cochrane Database Syst Rev (12): CD007950. doi:10.1002/14651858.CD007950.pub3. PMID 26662928.
^ 葉酸 - 素材情報データベース＜有効性情報＞（国立健康・栄養研究所）
^ 血液検査-巨赤芽球性貧血 1999/03/10の講義中国労災病院中央検査部
 ^ Goh YI & Koren G (2008) Folic acid in pregnancy and fetal outcomes. J Obstet Gynaecol 28, 3-13.
^ ⇒EC 1.5.1.3
^ Hoffbrand AV & Weir DG (2001) The history of folic acid. Br J Haematol 113, 579-589.
^ Appaji Rao N, Ambili M, Jala VR, Subramanya HS, Savithri HS (April 2003). “Structure-function relationship in serine hydroxymethyltransferase.”. Biochim. Biophys. Acta 1647 (1-2): 24?9. doi:10.1016/S1570-9639(03)00043-8. PMID 12686103.
^ Stover P, Schirch V (August 1990). ⇒“Serine hydroxymethyltransferase catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 5-formyltetrahydrofolate”. J. Biol. Chem. 265 (24): 14227?33. PMID 2201683. ⇒http://www.jbc.org/content/265/24/14227.short.
^ ⇒ENZYME: 2.1.2.1 KEGG
^ Duthie SJ (1999). ⇒“Folic acid deficiency and cancer: mechanisms of DNA instability”. Br. Med. Bull. 55 (3): 578-592. PMID 10746348. ⇒http://bmb.oxfordjournals.org/content/55/3/578.abstract.
^ Van Guelpen B (2007). “Folate in colorectal cancer, prostate cancer and cardiovascular disease”. Scand J Clin Lab Invest 67 (5): 459?73. doi:10.1080/00365510601161513. PMID 17763182.
^ Jennings E (1995). “Folic acid as a cancer-preventing agent”. Med Hypotheses 45 (3): 297?303. doi:10.1016/0306-9877(95)90121-3. PMID 8569555.
^ Ebbing M, Bonaa KH, Nygard O, et al. (2009). ⇒“Cancer incidence and mortality after treatment with folic acid and vitamin B12”. JAMA 302 (19): 2119–26. doi:10.1001/jama.2009.1622. PMID 19920236. ⇒http://jama.ama-assn.org/cgi/content/short/302/19/2119.
^ Kim YI (1 November 2004). ⇒“Will mandatory folic acid fortification prevent or promote cancer?”. Am J Clin Nutr 80 (5): 1123?8. PMID 15531657. ⇒http://www.ajcn.org/cgi/content/full/80/5/1123.
^ a b Ulrich American Journal of Clinical Nutrition, Vol. 86, No. 2, 271-273, August 2007 Folate and cancer prevention: a closer look at a complex picture
^ Sanjoaquin MA, Allen N, Couto E, Roddam AW, Key TJ (2005). “Folate intake and colorectal cancer risk: a meta-analytical approach”. Int J Cancer 113 (5): 825?8. doi:10.1002/ijc.20648. PMID 15499620.
^ Giovannucci E, Stampfer MJ, Colditz GA, et al. (1998). “Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study”. Ann. Intern. Med. 129 (7): 517?24. PMID 9758570.
^ Cole BF, Baron JA, Sandler RS et al. (2007). “Folic acid for the prevention of colorectal adenomas: a randomized clinical trial”. JAMA 297 (21): 2351?9. doi:10.1001/jama.297.21.2351. PMID 17551129.
^ a b Johansson M et al Feb 2008 17(2) Cancer Epidemiol Biomarkers Prev, Circulating Concentrations of Folate and Vitamin B12 in Relation to Prostate Cancer Risk: Results from the European Prospective Investigation into Cancer and Nutrition Study
^ Larsson SC, Hakansson N, Giovannucci E, Wolk A (2006). ⇒“Folate intake and pancreatic cancer incidence: a prospective study of Swedish women and men”. J Natl Cancer Inst 98 (6): 407?13. doi:10.1093/jnci/djj094. PMID 16537833. ⇒http://jnci.oxfordjournals.org/cgi/content/full/98/6/407.
^ Kim YI (2006). “Does a high folate intake increase the risk of breast cancer?”. Nutr Rev 64 (10 Pt 1): 468?75. doi:10.1301/nr.2006.oct.468-475. PMID 17063929.
^ Ericson U, Sonestedt E, Gullberg B, Olsson H, Wirfalt E (2007). “High folate intake is associated with lower breast cancer incidence in postmenopausal women in the Malmo Diet and Cancer cohort”. Am J Clin Nutr 86 (2): 434?43. PMID 17684216.
^ Zhang SM, Cook NR, Albert CM, Gaziano JM, Buring JE, Manson JE (November 2008). ⇒“Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trial”. JAMA 300 (17): 2012?21. doi:10.1001/jama.2008.555. PMC 2593624. PMID 18984888. ⇒http://jama.ama-assn.org/cgi/content/short/300/17/2012.
^ a b Zhang S et al, Vol. 281 No. 17, May 5, 1999, 1632-1637, JAMA, A Prospective Study of Folate Intake and the Risk of Breast Cancer
^ “ ⇒MedlinePlus: Folic Acid Supplements Raise Prostate Cancer Risk”. 2010年11月1日閲覧。
^ a b Figueiredo et al., 2009, "Folic acid and risk of prostate cancer: results from a randomized clinical trial"
^ Weinstein SJ et al Null Association Between Prostate Cancer and Serum Folate, Vitamin B6, Vitamin B12, and Homocysteine Vol 12 pg 1271-1272 Cancer Epidemiology, Biomarkers, & Prevention November 2003
^ a b figueiredo et al 2009 folic acid and risk of prostate cancer: results from a randomized clinical trial
^ a b c Hattori, Y; Maitani, Y (2005). ⇒“Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase.”. Cancer gene therapy 12 (10): 796?809. doi:10.1038/sj.cgt.7700844. PMID 15891776. ⇒http://www.nature.com/cgt/journal/v12/n10/pdf/7700844a.pdf.
^ "folic-acid and Xeloda Interactions"
^ Bailey SW, Ayling JE (September 2009). “The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake”. Proceedings of the National Academy of Sciences of the United States of America 106 (36): 15424?9. doi:10.1073/pnas.0902072106. PMC 2730961. PMID 19706381. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730961/.
^ a b Hazra, A; Selhub, J; Chao, WH; Ueland, PM; Hunter, DJ; Baron, JA (2010). “Uracil misincorporation into DNA and folic acid supplementation.”. The American journal of clinical nutrition 91 (1): 160?5. doi:10.3945/ajcn.2009.28527. PMC 2793107. PMID 19923375. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793107/.
^ a b Seto, SW; Lam, TY; Or, PM; Lee, WY; Au, AL; Poon, CC; Li, RW; Chan, SW et al. (2010). “Folic acid consumption reduces resistin level and restores blunted acetylcholine-induced aortic relaxation in obese/diabetic mice.”. The Journal of nutritional biochemistry 21 (9): 872?80. doi:10.1016/j.jnutbio.2009.06.015. PMID 19879746.

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