ナトリウムチャネル
^ a b “On the structural basis for size-selective permeation of organic cations through the voltage-gated sodium channel. Effect of alanine mutations at the DEKA locus on selectivity, inhibition by Ca2+ and H+, and molecular sieving”. The Journal of General Physiology 110 (6): 693?715. (December 1997). doi:10.1085/jgp.110.6.693. PMC 2229404. PMID 9382897. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229404/.
^ “Role of outer ring carboxylates of the rat skeletal muscle sodium channel pore in proton block”. The Journal of Physiology 543 (Pt 1): 71?84. (August 2002). doi:10.1113/jphysiol.2002.021014. PMC 2290475. PMID 12181282. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290475/.
^ “Acidosis differentially modulates inactivation in na(v)1.2, na(v)1.4, and na(v)1.5 channels”. Frontiers in Pharmacology 3: 109. (2012). doi:10.3389/fphar.2012.00109. PMC 3372088. PMID 22701426. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372088/.
^ “Proton sensors in the pore domain of the cardiac voltage-gated sodium channel”. The Journal of Biological Chemistry 288 (7): 4782?91. (February 2013). doi:10.1074/jbc.M112.434266. PMC 3576083. PMID 23283979. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576083/.
^ “Isoform-dependent interaction of voltage-gated sodium channels with protons”. The Journal of Physiology 576 (Pt 2): 493?501. (October 2006). doi:10.1113/jphysiol.2006.115659. PMC 1890365. PMID 16873405. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890365/.
^ “Blood and muscle pH after maximal exercise in man”. Journal of Applied Physiology 32 (3): 304?8. (March 1972). doi:10.1152/jappl.1972.32.3.304. PMID 5010039.
^ “A Mixed Periodic Paralysis & Myotonia Mutant, P1158S, Imparts pH-Sensitivity in Skeletal Muscle Voltage-gated Sodium Channels”. Scientific Reports 8 (1): 6304. (April 2018). Bibcode: 2018NatSR...8.6304G. doi:10.1038/s41598-018-24719-y. PMC 5908869. PMID 29674667. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908869/.
^ “Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3”. Channels 12 (1): 367?377. (October 2018). doi:10.1080/19336950.2018.1539611. PMC 6284583. PMID 30362397. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284583/.
^ “Evolution of voltage-gated ion channels at the emergence of Metazoa”. The Journal of Experimental Biology 218 (Pt 4): 515?25. (February 2015). doi:10.1242/jeb.110270. PMID 25696815.
^ “Evolution of sodium channels predates the origin of nervous systems in animals”. Proceedings of the National Academy of Sciences of the United States of America 108 (22): 9154?9. (May 2011). Bibcode: 2011PNAS..108.9154L. doi:10.1073/pnas.1106363108. PMC 3107268. PMID 21576472. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107268/.
^ “The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans”. Nature 451 (7180): 783?8. (February 2008). Bibcode: 2008Natur.451..783K. doi:10.1038/nature06617. PMC 2562698. PMID 18273011. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562698/.
^ a b “Molecular evolution of voltage-sensitive ion channel genes: on the origins of electrical excitability”. Molecular Biology and Evolution 10 (1): 221?42. (January 1993). doi:10.1093/oxfordjournals.molbev.a039986. PMID 7680747.
^ “Independent acquisition of sodium selectivity in bacterial and animal sodium channels”. Current Biology 23 (21): R948?9. (November 2013). doi:10.1016/j.cub.2013.09.025. PMID 24200318.
^ Voltage-Gated Sodium Channels: Evolutionary History and Distinctive Sequence Features. 78. (2016). 261?86. doi:10.1016/bs.ctm.2016.05.002. ISBN 9780128053867. PMID 27586287
^ a b “Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes”. Molecular Biology and Evolution 28 (1): 859?71. (January 2011). doi:10.1093/molbev/msq257. PMID 20924084.
^ a b “Expansion of voltage-dependent Na+ channel gene family in early tetrapods coincided with the emergence of terrestriality and increased brain complexity”. Molecular Biology and Evolution 28 (4): 1415?24. (April 2011). doi:10.1093/molbev/msq325. PMC 3058772. PMID 21148285. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058772/.
関連項目
イオンチャネル
カルシウムチャネル
カリウムチャネル
Two-pore-domainカリウムチャネル（英語版）
上皮性ナトリウムチャネル
クロナキシー（英語版）
高カリウム血症-薬剤の影響や挫滅症候群によって細胞膜外のカリウム濃度が過多になりナトリウムチャンネルが機能しなくなり不整脈-心不全を引き起こしやすくなる症状である。
外部リンク
Sodium Channels - MeSH・アメリカ国立医学図書館・生命科学用語シソーラス（英語）
“Voltage-Gated Sodium Channels”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 2019年11月24日閲覧。
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