セイアーはマサチューセッツ州ケンブリッジのケンブリッジ病院（英語版）で腹部の手術を受けた後、45歳で亡くなった。彼女が胆嚢疾患だったとする報道もある一方[7]、緊急の盲腸手術を受けていたとする説も存在する[1][2]。彼女の死から2年後、女性民主同盟のボストン支部はジェシー・ウッドロウ・セイアー女性民主同盟に改名された[8]。

彼女はペンシルベニア州ベスレヘムのニスキー・ヒル墓地に埋葬された[9]。
参考文献^ a b Doug Wead, " ⇒Upstairs at the White House ? List of Presidents' Kids -- Woodrow Wilson Archived 2010-08-23 at the Wayback Machine.," at upstairsatthewhitehouse.com, accessed 2010-01-26.
^ a b c d e f g h i j ⇒Princeton University Library Mudd Manuscript Library, Jessie Wilson Sayre Finding aid, accessed 2010-01-26.
^ a b c d "Miss Jessie Wilson to Wed F.B. Sayre; Engagement of President's Second Daughter to Assistant of Whitman Announced," The New York Times, 1913-07-03, p. 1.
^ "Stormy Voyage Marks Finish of Honeymoon Spent in Europe, The Milwaukee Sentinel, 1914-01-24 at p. 1.
^ a b Jessie Wilson biography Archived 2011-07-18 at the Wayback Machine., woodrowwilsonhouse.org, accessed 2010-01-26.
^ "Mrs. Jessie Sayre May Be Candidate for Senate Seat," The New Castle News New Castle, Pennsylvania, 1929-06-11 at p. 9.
^ " ⇒Milestones: Jan. 26, 1933," Time magazine, 1933-01-23
^ "Jessie Sayre Club Seeking a Charter," The New York Times, 1935-08-04 at N6.