セロトニントランスポーター遺伝子

SLC6A4

PDBに登録されている構造
 PDBオルソログ検索: ⇒RCSB PDBe PDBj

PDBのIDコード一覧

⇒5I6X, ⇒5I73, ⇒5I75, ⇒5I6Z, ⇒5I71, ⇒5I74

識別子
記号 ⇒SLC6A4, 5-HTT, 5HTT, HTT, OCD1, SERT, SERT1, hSERT, Solute Carrier Family 6 (neurotransmitter transporter), member 4, solute carrier family 6 member 4, 5-HTTLPR
外部IDOMIM: 182138 MGI: ⇒96285 HomoloGene: 817 GeneCards: SLC6A4

遺伝子の位置 (ヒト)

染色体17番染色体 (ヒト)[1]

バンドデータ無し開始点30,194,319 bp [1]
終点30,236,002 bp [1]

遺伝子の位置 (マウス)

染色体11番染色体 (マウス)[2]

バンドデータ無し開始点76,998,603 bp [2]
終点77,032,340 bp [2]

RNA発現パターン

⇒さらなる参照発現データ

遺伝子オントロジー
分子機能? ⇒cocaine binding
? ⇒nitric-oxide synthase binding
? ⇒protein homodimerization activity
? ⇒myosin binding
? ⇒syntaxin-1 binding
? ⇒metal ion binding
? ⇒neurotransmitter:sodium symporter activity
? ⇒actin filament binding
? ⇒monoamine transmembrane transporter activity
? ⇒Rab GTPase binding
? ⇒血漿タンパク結合
? ⇒serotonin transmembrane transporter activity
? ⇒symporter activity
? ⇒serotonin:sodium symporter activity
? ⇒dopamine:sodium symporter activity
? ⇒serotonin binding

細胞の構成要素? ⇒integral component of membrane
? ⇒細胞質基質
? ⇒エンドソーム
? ⇒membrane
? ⇒integral component of plasma membrane
? ⇒脂質ラフト
? ⇒neuron projection
? ⇒endosome membrane
? ⇒細胞内膜系
? ⇒presynapse
? ⇒細胞膜
? ⇒integral component of postsynaptic membrane
? ⇒integral component of presynaptic membrane
? ⇒serotonergic synapse
? ⇒焦点接着
? ⇒シナプス

生物学的プロセス? ⇒cellular response to organic substance
? ⇒cellular response to retinoic acid
? ⇒response to estradiol
? ⇒cellular response to cGMP
? ⇒response to hypoxia
? ⇒negative regulation of neuron differentiation
? ⇒射精
? ⇒response to nutrient
? ⇒血管収縮
? ⇒negative regulation of cerebellar granule cell precursor proliferation
? ⇒記憶
? ⇒monoamine transport
? ⇒response to organic substance
? ⇒brain development
? ⇒positive regulation of gene expression
? ⇒positive regulation of cell cycle
? ⇒serotonin transport
? ⇒protein oligomerization
? ⇒概日リズム
? ⇒膜輸送
? ⇒社会的行動
? ⇒serotonin uptake
? ⇒neurotransmitter transport
? ⇒negative regulation of organ growth
? ⇒protein homooligomerization
? ⇒response to toxic substance
? ⇒negative regulation of synaptic transmission, dopaminergic
? ⇒response to drug
? ⇒brain morphogenesis
? ⇒positive regulation of serotonin secretion
? ⇒neurotransmitter biosynthetic process
? ⇒dopamine uptake involved in synaptic transmission
? ⇒regulation of thalamus size

出典: ⇒Amigo / QuickGO

オルソログ
種ヒトマウス
Entrez